I think Wheedon is a good choice for this based off Angel and Buffy more than his Avengers work. I haven't been a fan of the DC movies yet so will see what he can do with it. Marvel fans that have turned on DC completely maybe will be more likely to give this one a chance with him on board.
btw MCU nearly 10 years in and no female directors or solo female films yet. Captain Marvel still 2 years away and y'all hating on this choice? really?