If you're an irresponsible dumbass on a particular subject-- in Kyrie's case, science-- then it's acceptable to call you an irresponsible dumbass. If he didn't want to be called an irresponsible dumbass, then there are exceedingly easy ways to clear that up.

I love Kyrie the player. I love Kyrie the activist. He's genuinely one of my favorite players of the last decade. But Kyrie the galaxy brain science weirdo is an irresponsible dumbass. And at this point, there's no real reason to defend it. He's a complex dude who does some indisputably good things. His decision to not get vaccinated-- and to be coy about it-- is not one of those things.