Moon
Primer
Sleep Dealer
Gattaca
Alien (the first one)
The Thing (sci-fi/horror)
Dark City (it's been a while since I've seen this though)
Solaris
Children of Men
Splice (save for Dren the monster, that was it in terms of special effects)
The Fly (save for jeff goldblum turning into a fly, the transporter and what not, it was limited also in special effects)

I can't think of any other ones at the moment...