The problem is they constantly want to "get in on the act" and shine, because they're comedians and they like the attention. So they keep on interrupting with jokes and non-sequiturs instead of just letting their guests talk. Because they don't have the in-depth knowledge and they want the podcast to ultimately still be about them.

I think that's why these guys are better with comedians, but they're speaking the same shared language and can directly relate to their experiences.