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Forum nameGeneral Discussion
Topic subjectOk..now THIS give me pause
Topic URLhttp://board.okayplayer.com/okp.php?az=show_topic&forum=4&topic_id=13439076&mesg_id=13439096
13439096, Ok..now THIS give me pause
Posted by rdhull, Thu Aug-05-21 12:41 PM
>I missed the news, but it's entered Phase 2 trials.
>
>If this works then COVID may be manageable. Imagine getting a
>positive test and taking a pill twice a day for 10 days that
>suppresses COVID replication so your immune system can take it
>out easier.
>
>Facui spoke about it here:
>https://www.csis.org/analysis/conversation-dr-anthony-fauci-antiviral-program-pandemics
>
>Biden's giving $3.2 billion:
>https://www.niaid.nih.gov/news-events/biden-administration-invest-3-billion-american-rescue-plan-part-covid-19-antiviral
>
>
>Swipe about pill:
>http://fool.com/investing/2021/08/03/this-could-be-pfizers-next-covid-blockbuster-and-i/
>
>Chief scientific officer Mikael Dolsten said that in the phase
>1 study, PF-07321332 exceeded the level predicted to inhibit
>coronavirus viral replication by more than fivefold. Dolsten
>also stated that the experimental protease inhibitor showed
>powerful antiviral activity in preclinical testing that could
>be effective against "all currently known COVID-19 variants."
>
>So far, the experimental antiviral drug appears to have a good
>safety profile. Dolsten said that there haven't been any
>safety issues in giving doses of up to 500 milligrams twice
>per day over a 10-day period.
>
>Based on these encouraging results, Pfizer advanced the oral
>protease inhibitor into phase 2/3 testing in July. The company
>will evaluate PF-07321332 in five-day and 10-day treatments
>for individuals who have been in close contact with someone
>with COVID-19.
>
>Coming soon?
>There shouldn't be a long wait for Pfizer's next potential
>COVID-19 blockbuster. Assuming the phase 2/3 testing goes
>well, the company thinks that it will be able to file for U.S.
>EUA in the fourth quarter of this year.