More than any particular issue, i just have immense respect for her overall integrity and case-by-case approach to issues.

And i think she would be kryptonite to Trump. She would utterly dismantle his fake tough-guy act. She wouldn't even have to say anything for everyone to know she's 1000 times tougher than him, and she isnt going to pearl-clutch and take the bait every one of his stupid tweets and insults, so he wont be able to paint her as some kind of wimpy pc-police sjw snowflake, which is his main political weapon.
She'll even call him a little bitch from time to time lol.

But she'll actually be focused on the issues and he'll have to wade into deeper substantive waters against her.