Does he have a life outside his work? Because if he has a wife and kids and great relationships with all of them AND he does everything else that he's so well known for in the medical community, then it really is game over.

I don't know anybody in medicine (who actually cares about global health care) who wouldn't love to be Farmer, but for most of us it just doesn't seem very realistic if you want to have a family and a life outside of your work.