Osiris Rising is a re-telling of the Osiris "myth", set in modern Africa. A young scholar activist, Auset, leaves the US and goes to the continent in search of an old college friend/flame, Ausar. Ausar is involved in the liberation struggle on the continent and another classmate of theirs, Set(h), has ascended to Minister of security and views Ausar and his comrades as the greatest threat to the regime.