Thanks to me cracking a program just now with iSerial Reader (thank you for that), it was suggested I use a firewall program called Little Snitch to keep the program from contacting it's website. So far, Little Snitch appears to be a nice lil firewall, allowing you to block pacific port traffic from particular programs and IP addresses.

Check it out here http://www.obdev.at/products/littlesnitch/index.html

And of course, iSerial Reader has a sn for that too.