I just scope enemies working headshots, then if anything comes close I switch to shotgun and deal with it. I enjoy handcannons, but I need the emphasis on the CANNON, so like Timur's Lash is my favorite handcannon to use lately (and no third eye and it's all right, but that's also because I have rodeo on it so I precision kill, reload, check the radar, then go back to ADS).

In PvP I run MIDA for the speed boost or Last Word because it's stupidly over-powered. I just lean on the radar a lot in PvE to track threats, basically, as I pick off what I consider either high value or easy return enemies first.