You see a stranger that you wanna make fun of
the jokes consist of
-how they walk
-how they talk
-what they look like
-et al easy shit

You have a acquaintance, the jokes consist of
-mannerisms
-likes and dislikes
-relationships they have with other aquantances
- etc

You have a close relationship
-hopes and fears
-deep call backs and references
-disposition
-personality
-history
-future
-etc

shit you can only develop by getting past surface level stereotypes. If you want jokes about misfortune, get granular.